SUBJECT

Registration

Welcome addresses:

- Stadtrat Wolfgang Laczny, City of Braunschweig
- Professor Dr. Rudi Balling, scientific director of the Helmholtz Centre for Infection Research

13:15 - 13:35

G. Della Gatta:
Systems Biology Approaches to Drug Discovery and Gene Function

13:35 - 13:55

M. Auer:
Integrating single bead, single compound, single molecule, & single cell technologies into a chemical genomics target validation proces

13:55 - 14:15

N. Johnsson:
Chemical and Biological Sensors to Measure Protein Secretion in Yeast

14:15 - 14:20

F. Christian:
Targeting Compartmentalised cAMP-dependent Signalling Pathways with Small Molecules

14:20 - 14:25

R. Fischer:
Quantative Phosphoproteiomics predicts Kinase Activities involved in E-cadherin signaling

14:25 - 14:45

Plenary discussion

14:45 - 15:15

Coffee break

A. Kirschning:
Expanding the Frontiers of Organic Synthesis by Engineered and Biology-Based Concepts

D. Menche:
Practical Methods for the Stereoselective Synthesis of Bioactive Amines

G. Müller:
Chemoproteomics in Protein Kinase Inhibitor Discovery:
From Targets to Compounds to Targets

T. Mayer:
Design and Synthesis of a "tag-free" chemical probe for photoaffinity labeling

J. Jung:
Synthesis and Structural Characterization of Polyubiquitin Conjugates Using High Resolutin Mass Spectrometry

Plenary discussion

16:45 - 17:45 POSTER SESSION

with drinks and snacks

Historical sight-seeing tour (optional, not included in fees)

Workshop Dinner at the old Gewandhaus (see map)

H. Kubinyi:
Chemical Biology and Chemogenomics in Drug Discovery

K. Kumar:
Biology Oriented Synthesis (BIOS) for Chemogenomics

J. Rademann:
ChemBioNet: Tools for HTS data analysis, documentation and library design

HP Deigner:
In-vivo and in-vitro investigation of Aspirin using pan genomic differential gene expression analysis

E. Missner:
Unveiling potential off-targets: Comprehensive selectivity profiling of a novel mulit-target protein kinase inhibitor by inhibitor affinity chromatography (IAC) using different strategies of immobilization

Plenary diskussion

Coffee break

L. Puskas:
Universal surface chemistry for capturing small molecules without linkers on glass slides

J. Scheuermann:
Encoded self-assembling chemical libraries, a novel tool in drug discovery

J. Hoheisel:
Microarray technology: new concepts and technologies

I. Block
High Complexity Peptide Libraries on Microchip

A. Wiemann
Advancement and application of high-density chemical microarrays to probe for protein drug interactions within SMP "Protein"

Plenary discussion

Farewell

Guided visits of the HZI Screening Facility